| 1937 | Born in Tudela, Navarra Spain |
| 1958-61 | Worked at the office of Francisco Javier Sáenz de Oiza |
| 1961 | Obtained degree from the Escuela Técnica Superior, Madrid |
| 1962 | Worked at the office of Jǿrn Utzon, Denmark |
| 1963 | Spent two years at the Spanish Academy, Rome |
| 1967 | Diestre Factory, Zaragoza, Spain |
| 1976 | Bankinter (Bank) in Madrid |
| 1981 | City Hall of Logrono, Spain |
| 1985-90 | Dean at the Harvard University Graduate School of Design |
| 1986 | National Museum of Roman Art, Mérida, Spain |
| 1987 | L’Illa Diagonal, Barcelona, Spain, in collaboration with Manuel Solà-Morales |
| 1990 | Kursaal Auditorium and Congress Center, San Sebastián, Spain |
| 1991 | Murcia City Hall Extension, Spain San Pablo Airport, Seville, Spain |
| 1992 | Madrid Atocha railway station The Pilar and Joan Miro Foundation, Palma de Mallorca, Spain |
| 1996 | Pritzker Architecture Prize Souks, Beirut, Lebanon |
| 1998 | Moderna Museet and Swedish Centre for Architecture and Design, Stockholm, Sweden |
| 2000 | Audrey Jones Beck Building, Houston, Texas |
| 2001 | Iesu Church, San Sebastián, Spain |
| 2002 | Cathedral of Our Lady of the Angels, Los Angeles, California |
| 2003 | RIBA Royal Gold Medal |
| 2005 | Northwest Corner Building, Columbia University, New York, USA, in collaboration with Moneo-Brock Studio |
| 2007 | Museo del Prado extension, Madrid, Spain Neuroscience Institute and Department of Psychology, Princeton University, USA |
| 2009 | New Library of the University of Deusto, Bilbao, Basque Country, Spain |
| 2012 | Thomas Jefferson Medal in Architecture Prince of Asturias Award for the Arts |
| 2015 2017 | Museum University of Navarra, Pamplona, Spain Praemium Imperiale |